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  • Targeting keratin 17-mediated reprogramming of de novo pyrimidine biosynthesis to overcome chemoresistance in pancreatic cancer

  • Chun-Hao Pan, Nina V. Chaika, Robert Tseng, Md Afjalus Siraj, Bo Chen, Katie L. Donnelly, Michael Horowitz, Cindy V. Leiton, Sumedha Chowdhury, Lucia Roa-Peña, Lyanne Oblein, Natalia Marchenko, Pankaj K. Singh, Kenneth R. Shroyer, Luisa F. Escobar-Hoyos

       bioRxiv 2022.08.24.504873; doi:

  • Disassembly of embryonic keratin filaments promotes pancreatic cancer metastases

  • Ryan R. Kawalerski, Mariana Torrente Gonçalves, Chun-Hao Pan, Robert Tseng, Lucia Roa-Peña, Cindy V.        Leiton, Luke A. Torre-Healy, Taryn Boyle, Sumedha Chowdhury, Natasha T. Snider, Kenneth R. Shroyer, Luisa F. Escobar-Hoyos

  • Baraks G, Tseng R, Pan CH, Kasliwal S, Leiton CV, Shroyer KR, Escobar-Hoyos LF. Dissecting the Oncogenic Roles of Keratin 17 in the Hallmarks of Cancer. Cancer Res. 2022 Apr 1;82(7):1159-1166. doi: 10.1158/0008-5472.CAN-21-2522. PMID: 34921015; PMCID: PMC9016724.

  • Sruthi Babu, MD, PhD, Nam W Kim, PhD, Maoxin Wu, MD, PhD, Ina Chan, Luisa F Escobar-Hoyos, PhD, Kenneth R Shroyer, MD, PhD, Keratin 17 Is a Novel Cytologic Biomarker for Urothelial Carcinoma Diagnosis,  American Journal of Clinical Pathology, Volume 156, Issue 5, November 2021, Pages 926–933,

  • Roa-Peña L, Babu S, Leiton CV, Wu M, Taboada S, Akalin A, Buscaglia J, Escobar-Hoyos LF, Shroyer KR. Keratin 17 testing in pancreatic cancer needle aspiration biopsies predicts survival. Cancer Cytopathol. 2021 Nov;129(11):865-873. doi: 10.1002/cncy.22438. Epub 2021 Jun 2. PMID: 34076963; PMCID: PMC9014629.

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